Coiled-coil domain-containing protein 121 (CCDC121)

About Coiled-coil domain-containing protein 121

Coiled-coil domain-containing protein 121 (CCDC121) is a protein from Homo sapiens identified by UniProt accession Q6ZUS5, 278 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	Coiled-coil domain-containing protein 121
UniProt accession	Q6ZUS5
Gene	CCDC121
Organism	Homo sapiens
Length	278 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (28)

Diseases linked to this target (Open Targets).

IGF-1 measurement · score 0.12
creatinine measurement · score 0.12
triglyceride measurement · score 0.08
metabolic syndrome · score 0.08
systolic blood pressure · score 0.08
alcohol consumption measurement · score 0.07
phospholipid measurement · score 0.06
oral cavity cancer · score 0.06
hemoglobin measurement · score 0.06
prostate carcinoma · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6ZUS5-F1	alphafold	PREDICTED	87.50	—

Amino-acid sequence (278 residues)

MTDLNKHIKQ AQTQRKQLLE ESRELHREKL LVQAENRFFL EYLTNKTEEY TEQPEKVWNS YLQKSGEIER RRQESASRYA EQISVLKTAL LQKENIQSSL KRKLQAMRDI AILKEKQEKE IQTLQEETKK VQAETASKTR EVQAQLLQEK RLLEKQLSEP DRRLLGKRKR RELNMKAQAL KLAAKRFIFE YSCGINRENQ QFKKELLQLI EQAQKLTATQ SHLENRKQQL QQEQWYLESL IQARQRLQGS HNQCLNRQDV PKTTPSLPQG TKSRINPK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards