Tubulin epsilon and delta complex protein 2 (TEDC2)

About Tubulin epsilon and delta complex protein 2

Tubulin epsilon and delta complex protein 2 (TEDC2) is a protein from Homo sapiens identified by UniProt accession Q7L2K0, 433 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

Target properties

Protein name	Tubulin epsilon and delta complex protein 2
UniProt accession	Q7L2K0
Gene	TEDC2
Organism	Homo sapiens
Length	433 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (30)

Diseases linked to this target (Open Targets).

lung adenocarcinoma · score 0.08
neoplasm · score 0.08
Griscelli syndrome type 3 · score 0.05
hepatocellular carcinoma · score 0.05
uncombable hair syndrome · score 0.04
Griscelli disease type 3 · score 0.04
Griscelli disease · score 0.04
oculocutaneous albinism type 3 · score 0.04
Griscelli disease type 1 · score 0.04
non-small cell lung carcinoma · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q7L2K0-F1	alphafold	PREDICTED	67.10	—

Amino-acid sequence (433 residues)

MLPAGCSRRL VAELQGALDA CAQRQLQLEQ SLRVCRRLLH AWEPTGTRAL KPPPGPETNG EDPLPACTPS PQDLKELEFL TQALEKAVRV RRGITKAGER DKAPSLKSRS IVTSSGTTAS APPHSPGQAG GHASDTRPTK GLRQTTVPAK GHPERRLLSV GDGTRVGMGA RTPRPGAGLR DQQMAPSAAP QAPEAFTLKE KGHLLRLPAA FRKAASQNSS LWAQLSSTQT SDSTDAAAAK TQFLQNMQTA SGGPQPRLSA VEVEAEAGRL RKACSLLRLR MREELSAAPM DWMQEYRCLL TLEGLQAMVG QCLHRLQELR AAVAEQPPRP CPVGRPPGAS PSCGGRAEPA WSPQLLVYSS TQELQTLAAL KLRVAVLDQQ IHLEKVLMAE LLPLVSAAQP QGPPWLALCR AVHSLLCEGG ARVLTILRDE PAV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards