Hsp90 co-chaperone Cdc37-like 1 (CDC37L1)

About Hsp90 co-chaperone Cdc37-like 1

Hsp90 co-chaperone Cdc37-like 1 (CDC37L1) is a protein from Homo sapiens identified by UniProt accession Q7L3B6, 337 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.

Target properties

Protein name	Hsp90 co-chaperone Cdc37-like 1
UniProt accession	Q7L3B6
Gene	CDC37L1
Organism	Homo sapiens
Length	337 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (64)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.38
mean reticulocyte volume · score 0.31
reticulocyte measurement · score 0.27
breast adenocarcinoma · score 0.25
platelet crit · score 0.23
erythrocyte count · score 0.20
platelet count · score 0.11
mean corpuscular volume · score 0.09
hepatocellular carcinoma · score 0.08
mean corpuscular hemoglobin · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q7L3B6-F1	alphafold	PREDICTED	71.74	—

Amino-acid sequence (337 residues)

MEQPWPPPGP WSLPRAEGEA EEESDFDVFP SSPRCPQLPG GGAQMYSHGI ELACQKQKEF VKSSVACKWN LAEAQQKLGS LALHNSESLD QEHAKAQTAV SELRQREEEW RQKEEALVQR EKMCLWSTDA ISKDVFNKSF INQDKRKDTE DEDKSESFMQ KYEQKIRHFG MLSRWDDSQR FLSDHPYLVC EETAKYLILW CFHLEAEKKG ALMEQIAHQA VVMQFIMEMA KNCNVDPRGC FRLFFQKAKA EEEGYFEAFK NELEAFKSRV RLYSQSQSFQ PMTVQNHVPH SGVGSIGLLE SLPQNPDYLQ YSISTALCSL NSVVHKEDDE PKMMDTV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards