Fc receptor-like A (FCRLA)

About Fc receptor-like A

Fc receptor-like A (FCRLA) is a protein from Homo sapiens identified by UniProt accession Q7L513, 359 residues long. MolForge cross-references it against 0 known binders and 126 disease associations.

Target properties

Protein name	Fc receptor-like A
UniProt accession	Q7L513
Gene	FCRLA
Organism	Homo sapiens
Length	359 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (126)

Diseases linked to this target (Open Targets).

lymphocyte count · score 0.37
total blood protein measurement · score 0.36
aspartate aminotransferase measurement · score 0.31
blood protein measurement · score 0.29
serum gamma-glutamyl transferase measurement · score 0.27
erythrocyte count · score 0.27
serum alanine aminotransferase measurement · score 0.23
low affinity immunoglobulin gamma Fc region receptor II-a/b measurement · score 0.22
alkaline phosphatase measurement · score 0.22
albumin:globulin ratio measurement · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q7L513-F1	alphafold	PREDICTED	75.20	—

Amino-acid sequence (359 residues)

MKLGCVLMAW ALYLSLGVLW VAQMLLAASF ETLQCEGPVC TEESSCHTED DLTDAREAGF QVKAYTFSEP FHLIVSYDWL ILQGPAKPVF EGDLLVLRCQ AWQDWPLTQV TFYRDGSALG PPGPNREFSI TVVQKADSGH YHCSGIFQSP GPGIPETASV VAITVQELFP APILRAVPSA EPQAGSPMTL SCQTKLPLQR SAARLLFSFY KDGRIVQSRG LSSEFQIPTA SEDHSGSYWC EAATEDNQVW KQSPQLEIRV QGASSSAAPP TLNPAPQKSA APGTAPEEAP GPLPPPPTPS SEDPGFSSPL GMPDPHLYHQ MGLLLKHMQD VRVLLGHLLM ELRELSGHRK PGTTKATAE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards