About Carbohydrate sulfotransferase 15
Carbohydrate sulfotransferase 15 (CHST15) is a protein
from Homo sapiens identified by UniProt accession
Q7LFX5, 561 residues long.
MolForge cross-references it against 0 known binders and
78 disease associations.
Target properties
| Protein name | Carbohydrate sulfotransferase 15 |
|---|
| UniProt accession | Q7LFX5 |
|---|
| Gene | CHST15 |
|---|
| Organism | Homo sapiens |
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| Length | 561 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (78)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.33
- lymphocyte count · score 0.33
- daytime rest measurement · score 0.32
- neurodegenerative disease · score 0.25
- ulcer disease · score 0.09
- proctitis · score 0.09
- cancer · score 0.08
- neoplasm · score 0.08
- esophageal squamous cell carcinoma · score 0.08
- chronic myeloproliferative disorder · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7LFX5-F1 | alphafold | PREDICTED | 79.56 | — |
Amino-acid sequence (561 residues)
MRHCINCCIQ LLPDGAHKQQ VNCQGGPHHG HQACPTCKGE NKILFRVDSK QMNLLAVLEV RTEGNENWGG FLRFKKGKRC SLVFGLIIMT LVMASYILSG AHQELLISSP FHYGGFPSNP SLMDSENPSD TKEHHHQSSV NNISYMKDYP SIKLIINSIT TRIEFTTRQL PDLEDLKKQE LHMFSVIPNK FLPNSKSPCW YEEFSGQNTT DPYLTNSYVL YSKRFRSTFD ALRKAFWGHL AHAHGKHFRL RCLPHFYIIG QPKCGTTDLY DRLRLHPEVK FSAIKEPHWW TRKRFGIVRL RDGLRDRYPV EDYLDLFDLA AHQIHQGLQA SSAKEQSKMN TIIIGEASAS TMWDNNAWTF FYDNSTDGEP PFLTQDFIHA FQPNARLIVM LRDPVERLYS DYLYFASSNK SADDFHEKVT EALQLFENCM LDYSLRACVY NNTLNNAMPV RLQVGLYAVY LLDWLSVFDK QQFLILRLED HASNVKYTMH KVFQFLNLGP LSEKQEALMT KSPASNARRP EDRNLGPMWP ITQKILRDFY RPFNARLAQV LADEAFAWKT T
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