About Peroxiredoxin-like 2C
Peroxiredoxin-like 2C (PRXL2C) is a protein
from Homo sapiens identified by UniProt accession
Q7RTV5, 226 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Peroxiredoxin-like 2C |
|---|
| UniProt accession | Q7RTV5 |
|---|
| Gene | PRXL2C |
|---|
| Organism | Homo sapiens |
|---|
| Length | 226 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- mean reticulocyte volume · score 0.04
- mean corpuscular volume · score 0.04
- platelet count · score 0.03
- intelligence · score 0.03
- hypertension · score 0.02
- appendicular lean mass · score 0.02
- grip strength measurement · score 0.02
- gut microbiome measurement · score 0.02
- vital capacity · score 0.02
- forced expiratory volume · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7RTV5-F1 | alphafold | PREDICTED | 83.57 | — |
Amino-acid sequence (226 residues)
MAAPAPVTRQ VSGAAALVPA PSGPDSGQPL AAAVAELPVL DARGQRVPFG ALFRERRAVV VFVRHFLCYI CKEYVEDLAK IPRSFLQEAN VTLIVIGQSS YHHIEPFCKL TGYSHEIYVD PEREIYKRLG MKRGEEIASS GQSPHIKSNL LSGSLQSLWR AVTGPLFDFQ GDPAQQGGTL ILGPGNNIHF IHRDRNRLDH KPINSVLQLV GVQHVNFTNR PSVIHV
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