About PTB-containing, cubilin and LRP1-interacting protein
PTB-containing, cubilin and LRP1-interacting protein (PID1) is a protein
from Homo sapiens identified by UniProt accession
Q7Z2X4, 250 residues long.
MolForge cross-references it against 0 known binders and
85 disease associations.
Target properties
| Protein name | PTB-containing, cubilin and LRP1-interacting protein |
| UniProt accession | Q7Z2X4 |
| Gene | PID1 |
| Organism | Homo sapiens |
| Length | 250 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (85)
Diseases linked to this target (Open Targets).
- coronary artery disease · score 0.38
- blood phosphate measurement · score 0.38
- Antimigraine preparation use measurement · score 0.37
- cortical surface area measurement · score 0.37
- high density lipoprotein cholesterol measurement · score 0.37
- blood protein measurement · score 0.34
- angina pectoris · score 0.30
- myocardial infarction · score 0.30
- BMI-adjusted hip circumference · score 0.30
- coffee consumption · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q7Z2X4-F1 | alphafold | PREDICTED | 67.29 | — |
Amino-acid sequence (250 residues)
MFSLPLSLPL CEDTAFLPSK CCSSHKTIKQ ARTLIMIFLA SGTHFQTMLK SKLNVLTLKK EPLPAVIFHE PEAIELCTTT PLMKTRTHSG CKVTYLGKVS TTGMQFLSGC TEKPVIELWK KHTLAREDVF PANALLEIRP FQVWLHHLDH KGEATVHMDT FQVARIAYCT ADHNVSPNIF AWVYREINDD LSYQMDCHAV ECESKLEAKK LAHAMMEAFR KTFHSMKSDG RIHSNSSSEE VSQELESDDG
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