PTB-containing, cubilin and LRP1-interacting protein (PID1)

Homo sapiens — UniProt Q7Z2X4

Gene: PID1Homo sapiensSwissProt reviewed

About PTB-containing, cubilin and LRP1-interacting protein

PTB-containing, cubilin and LRP1-interacting protein (PID1) is a protein from Homo sapiens identified by UniProt accession Q7Z2X4, 250 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.

Target properties

Protein namePTB-containing, cubilin and LRP1-interacting protein
UniProt accessionQ7Z2X4
GenePID1
OrganismHomo sapiens
Length250 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (85)

Diseases linked to this target (Open Targets).

  • coronary artery disease · score 0.38
  • blood phosphate measurement · score 0.38
  • Antimigraine preparation use measurement · score 0.37
  • cortical surface area measurement · score 0.37
  • high density lipoprotein cholesterol measurement · score 0.37
  • blood protein measurement · score 0.34
  • angina pectoris · score 0.30
  • myocardial infarction · score 0.30
  • BMI-adjusted hip circumference · score 0.30
  • coffee consumption · score 0.30

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q7Z2X4-F1alphafoldPREDICTED67.29—

Amino-acid sequence (250 residues)

MFSLPLSLPL CEDTAFLPSK CCSSHKTIKQ ARTLIMIFLA SGTHFQTMLK SKLNVLTLKK EPLPAVIFHE PEAIELCTTT PLMKTRTHSG CKVTYLGKVS TTGMQFLSGC TEKPVIELWK KHTLAREDVF PANALLEIRP FQVWLHHLDH KGEATVHMDT FQVARIAYCT ADHNVSPNIF AWVYREINDD LSYQMDCHAV ECESKLEAKK LAHAMMEAFR KTFHSMKSDG RIHSNSSSEE VSQELESDDG

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Quick facts

UniProtQ7Z2X4
GenePID1
OrganismHomo sapiens
Length250
Binders0
Diseases85
View on UniProt