About PABIR family member 2
PABIR family member 2 (PABIR2) is a protein
from Homo sapiens identified by UniProt accession
Q7Z309, 247 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | PABIR family member 2 |
|---|
| UniProt accession | Q7Z309 |
|---|
| Gene | PABIR2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 247 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- amelogenesis imperfecta · score 0.05
- tooth agenesis · score 0.05
- kidney cancer · score 0.04
- Hepatic veno-occlusive disease - immunodeficiency · score 0.04
- dentinogenesis imperfecta · score 0.04
- autoinflammation with episodic fever and lymphadenopathy · score 0.04
- Burkitts lymphoma · score 0.03
- Testicular regression syndrome · score 0.03
- idiopathic hypereosinophilic syndrome · score 0.03
- Mantle cell lymphoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7Z309-F1 | alphafold | PREDICTED | 59.96 | — |
Amino-acid sequence (247 residues)
MAQEKMELDL EPDTSYGGTL RRSSSAPLIH GLSDLSQVFQ PYTLRTRRNS TTIMSRHSLE EGLDMVNRET AHEREMQTAM QISQSWDESL SLSDSDFDKP EKLYSPKRID FTPVSPAPSP TRGFGKMFVS SSGLPPSPVP SPRRFSRRSQ SPVKCIRPSV LGPLKRKGEM ETESQPKRLF QGTTNMLSPD AAQLSDLSSC SDILDGSSSS SGLSSDPLAK GSATAESPVA CSNSCSSFIL MDDLSPK
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