About Sorting nexin-20
Sorting nexin-20 (SNX20) is a protein
from Homo sapiens identified by UniProt accession
Q7Z614, 316 residues long.
MolForge cross-references it against 0 known binders and
69 disease associations.
Target properties
| Protein name | Sorting nexin-20 |
|---|
| UniProt accession | Q7Z614 |
|---|
| Gene | SNX20 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 316 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (69)
Diseases linked to this target (Open Targets).
- inflammatory bowel disease · score 0.49
- Crohn's disease · score 0.46
- leprosy · score 0.35
- lymphocyte count · score 0.20
- diabetes mellitus · score 0.15
- endocrine system disease · score 0.14
- thyroid disease · score 0.14
- hypothyroidism · score 0.14
- Parkinson disease · score 0.13
- lung adenocarcinoma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7Z614-F1 | alphafold | PREDICTED | 82.97 | — |
Amino-acid sequence (316 residues)
MASPEHPGSP GCMGPITQCT ARTQQEAPAT GPDLPHPGPD GHLDTHSGLS SNSSMTTREL QQYWQNQKCR WKHVKLLFEI ASARIEERKV SKFVVYQIIV IQTGSFDNNK AVLERRYSDF AKLQKALLKT FREEIEDVEF PRKHLTGNFA EEMICERRRA LQEYLGLLYA IRCVRRSREF LDFLTRPELR EAFGCLRAGQ YPRALELLLR VLPLQEKLTA HCPAAAVPAL CAVLLCHRDL DRPAEAFAAG ERALQRLQAR EGHRYYAPLL DAMVRLAYAL GKDFVTLQER LEESQLRRPT PRGITLKELT VREYLH
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