About Stimulated by retinoic acid gene 8 protein homolog
Stimulated by retinoic acid gene 8 protein homolog (STRA8) is a protein
from Homo sapiens identified by UniProt accession
Q7Z7C7, 330 residues long.
MolForge cross-references it against 0 known binders and
107 disease associations.
Target properties
| Protein name | Stimulated by retinoic acid gene 8 protein homolog |
|---|
| UniProt accession | Q7Z7C7 |
|---|
| Gene | STRA8 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 330 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (107)
Diseases linked to this target (Open Targets).
- serum alanine aminotransferase measurement · score 0.32
- serum albumin measurement · score 0.30
- alkaline phosphatase measurement · score 0.13
- azoospermia · score 0.09
- body height · score 0.09
- male infertility with teratozoospermia due to single gene mutation · score 0.08
- partial chromosome Y deletion · score 0.08
- spermatogenic failure 8 · score 0.07
- spermatogenic failure 48 · score 0.07
- spermatogenic failure 61 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7Z7C7-F1 | alphafold | PREDICTED | 63.17 | — |
Amino-acid sequence (330 residues)
MGKIDVDKIL FFNQEIRLWQ LIMATPEENS NPHDRATPQL PAQLQELEHR VARRRLSQAR HRATLAALFN NLRKTVYSQS DLIASKWQVL NKAKSHIPEL EQTLDNLLKL KASFNLEDGH ASSLEEVKKE YASMYSGNDS FPQNGSSPWY LNFYKQTMDL LTGSGIITPQ EAALPIVSAA ISHLWQNLSE ERKASLRQAW AQKHRGPATL AEACREPACA EGSVKDSGVD SQGASCSLVS TPEEILFEDA FDVASFLDKS EVPSTSSSSS VLASCNPENP EEKFQLYMQI INFFKGLSCA NTQVKQEASF PVDEEMIMLQ CTETFDDEDL
Explore Stimulated by retinoic acid gene 8 protein homolog with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets