About Zinc finger protein 467
Zinc finger protein 467 (ZNF467) is a protein
from Homo sapiens identified by UniProt accession
Q7Z7K2, 595 residues long.
MolForge cross-references it against 0 known binders and
67 disease associations.
Target properties
| Protein name | Zinc finger protein 467 |
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| UniProt accession | Q7Z7K2 |
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| Gene | ZNF467 |
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| Organism | Homo sapiens |
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| Length | 595 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (67)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.35
- C-reactive protein measurement · score 0.29
- DNA methylation · score 0.29
- pulse pressure measurement · score 0.28
- mean platelet volume · score 0.13
- breast adenocarcinoma · score 0.11
- lymphocyte percentage of leukocytes · score 0.09
- melorheostosis with osteopoikilosis · score 0.05
- hyperostosis corticalis generalisata · score 0.05
- Hypocalcemic vitamin D-resistant rickets · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7Z7K2-F1 | alphafold | PREDICTED | 64.69 | — |
Amino-acid sequence (595 residues)
MRETLEALSS LGFSVGQPEM APQSEPREGS HNAQEQMSSS REERALGVCS GHEAPTPEEG AHTEQAEAPC RGQACSAQKA QPVGTCPGEE WMIRKVKVED EDQEAEEEVE WPQHLSLLPS PFPAPDLGHL AAAYKLEPGA PGALSGLALS GWGPMPEKPY GCGECERRFR DQLTLRLHQR LHRGEGPCAC PDCGRSFTQR AHMLLHQRSH RGERPFPCSE CDKRFSKKAH LTRHLRTHTG ERPYPCAECG KRFSQKIHLG SHQKTHTGER PFPCTECEKR FRKKTHLIRH QRIHTGERPY QCAQCARSFT HKQHLVRHQR VHQTAGPARP SPDSSASPHS TAPSPTPSFP GPKPFACSDC GLSFGWKKNL ATHQCLHRSE GRPFGCDECA LGATVDAPAA KPLASAPGGP GCGPGSDPVV PQRAPSGERS FFCPDCGRGF SHGQHLARHP RVHTGERPFA CTQCDRRFGS RPNLVAHSRA HSGARPFACA QCGRRFSRKS HLGRHQAVHT GSRPHACAVC ARSFSSKTNL VRHQAIHTGS RPFSCPQCGK SFSRKTHLVR HQLIHGEAAH AAPDAALAAP AWSAPPEVAP PPLFF
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