Serpin A11 (SERPINA11)

About Serpin A11

Serpin A11 (SERPINA11) is a protein from Homo sapiens identified by UniProt accession Q86U17, 422 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Serpin A11
UniProt accession	Q86U17
Gene	SERPINA11
Organism	Homo sapiens
Length	422 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.32
blood protein measurement · score 0.31
pleural effusion · score 0.27
pericardial effusion · score 0.27
Non-immune hydrops fetalis · score 0.11
hepatocellular carcinoma · score 0.09
neoplasm · score 0.07
kallistatin measurement · score 0.03
monocyte percentage of leukocytes · score 0.02
colorectal cancer · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86U17-F1	alphafold	PREDICTED	82.48	—

Amino-acid sequence (422 residues)

MGPAWLWLLG TGILASVHCQ PLLAHGDKSL QGPQPPRHQL SEPAPAYHRI TPTITNFALR LYKELAADAP GNIFFSPVSI STTLALLSLG AQANTSALIL EGLGFNLTET PEADIHQGFR SLLHTLALPS PKLELKVGNS LFLDKRLKPR QHYLDSIKEL YGAFAFSANF TDSVTTGRQI NDYLRRQTYG QVVDCLPEFS QDTFMVLANY IFFKAKWKHP FSRYQTQKQE SFFVDERTSL QVPMMHQKEM HRFLYDQDLA CTVLQIEYRG NALALLVLPD PGKMKQVEAA LQPQTLRKWG QLLLPSLLDL HLPRFSISGT YNLEDILPQI GLTNILNLEA DFSGVTGQLN KTISKVSHKA MVDMSEKGTE AGAASGLLSQ PPSLNTMSDP HAHFNRPFLL LLWEVTTQSL LFLGKVVNPV AG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards