Protein FAM83A (FAM83A)

About Protein FAM83A

Protein FAM83A (FAM83A) is a protein from Homo sapiens identified by UniProt accession Q86UY5, 434 residues long. MolForge cross-references it against 0 known binders and 86 disease associations.

Target properties

Protein name	Protein FAM83A
UniProt accession	Q86UY5
Gene	FAM83A
Organism	Homo sapiens
Length	434 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (86)

Diseases linked to this target (Open Targets).

mean corpuscular volume · score 0.25
lean body mass · score 0.13
non-small cell lung carcinoma · score 0.12
body mass index · score 0.12
lung adenocarcinoma · score 0.12
body weight · score 0.11
MODY · score 0.11
neoplasm · score 0.10
breast cancer · score 0.10
type 2 diabetes mellitus · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86UY5-F1	alphafold	PREDICTED	72.45	—

Amino-acid sequence (434 residues)

MSRSRHLGKI RKRLEDVKSQ WVRPARADFS DNESARLATD ALLDGGSEAY WRVLSQEGEV DFLSSVEAQY IQAQAREPPC PPDTLGGAEA GPKGLDSSSL QSGTYFPVAS EGSEPALLHS WASAEKPYLK EKSSATVYFQ TVKHNNIRDL VRRCITRTSQ VLVILMDVFT DVEIFCDILE AANKRGVFVC VLLDQGGVKL FQEMCDKVQI SDSHLKNISI RSVEGEIYCA KSGRKFAGQI REKFIISDWR FVLSGSYSFT WLCGHVHRNI LSKFTGQAVE LFDEEFRHLY ASSKPVMGLK SPRLVAPVPP GAAPANGRLS SSSGSASDRT SSNPFSGRSA GSHPGTRSVS ASSGPCSPAA PHPPPPPRFQ PHQGPWGAPS PQAHLSPRPH DGPPAAVYSN LGAYRPTRLQ LEQLGLVPRL TPTWRPFLQA SPHF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards