About Spermatogenesis-associated protein 24
Spermatogenesis-associated protein 24 (SPATA24) is a protein
from Homo sapiens identified by UniProt accession
Q86W54, 205 residues long.
MolForge cross-references it against 0 known binders and
80 disease associations.
Target properties
| Protein name | Spermatogenesis-associated protein 24 |
|---|
| UniProt accession | Q86W54 |
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| Gene | SPATA24 |
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| Organism | Homo sapiens |
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| Length | 205 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (80)
Diseases linked to this target (Open Targets).
- hypertrophic cardiomyopathy · score 0.12
- early-onset non-syndromic cataract · score 0.10
- electrocardiography · score 0.10
- hereditary hyperferritinemia with congenital cataracts · score 0.08
- isolated ectopia lentis · score 0.08
- Posterior polar cataract · score 0.08
- Total congenital cataract · score 0.07
- Cataract-microcornea syndrome · score 0.07
- cataract 13 with adult I phenotype · score 0.07
- cataract 38 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86W54-F1 | alphafold | PREDICTED | 88.42 | — |
Amino-acid sequence (205 residues)
MATPLGWSKA GSGSVCLALD QLRDVIESQE ELIHQLRNVM VLQDENFVSK EEFQAVEKKL VEEKAAHAKT KVLLAKEEEK LQFALGEVEV LSKQLEKEKL AFEKALSSVK SKVLQESSKK DQLITKCNEI ESHIIKQEDI LNGKENEIKE LQQVISQQKQ IFRNHMSDFR IQKQQESYMA QVLDQKHKKA SGTRQARSHQ HPREK
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