About Transmembrane protein 17
Transmembrane protein 17 (TMEM17) is a protein
from Homo sapiens identified by UniProt accession
Q86X19, 198 residues long.
MolForge cross-references it against 0 known binders and
52 disease associations.
Target properties
| Protein name | Transmembrane protein 17 |
|---|
| UniProt accession | Q86X19 |
|---|
| Gene | TMEM17 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 198 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (52)
Diseases linked to this target (Open Targets).
- prostate carcinoma · score 0.42
- platelet component distribution width · score 0.39
- mathematical ability · score 0.36
- Crohn's disease · score 0.32
- cigarettes per day measurement · score 0.32
- mean platelet volume · score 0.32
- neurodegenerative disease · score 0.29
- risky sexual behaviour measurement · score 0.29
- schizophrenia · score 0.27
- ankylosing spondylitis · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86X19-F1 | alphafold | PREDICTED | 85.76 | — |
Amino-acid sequence (198 residues)
MELPDPVRQR LGNFSRAVFS DSNRTGPESN EGPENEMVSS LALQMSLYFN TYYFPLWWVS SIMMLHMKYS ILPDYYKFIV ITVIILITLI EAIRLYLGYV GNLQEKVPEL AGFWLLSLLL QLPLILFLLF NEGLTNLPLE KAIHIIFTLF LAFQVVAAFL TLRKMVNQLA VRFHLQDFDR LSANRGDMRR MRSCIEEI
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