About GAS2-like protein 3
GAS2-like protein 3 (GAS2L3) is a protein
from Homo sapiens identified by UniProt accession
Q86XJ1, 694 residues long.
MolForge cross-references it against 0 known binders and
131 disease associations.
Target properties
| Protein name | GAS2-like protein 3 |
|---|
| UniProt accession | Q86XJ1 |
|---|
| Gene | GAS2L3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 694 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (131)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.13
- testosterone measurement · score 0.10
- alkaline phosphatase measurement · score 0.09
- low density lipoprotein cholesterol measurement · score 0.09
- hypertrophic cardiomyopathy · score 0.07
- left ventricular noncompaction · score 0.06
- dilated cardiomyopathy · score 0.05
- hepatocellular carcinoma · score 0.05
- Sensorineural deafness with dilated cardiomyopathy · score 0.05
- dilated cardiomyopathy 1M · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86XJ1-F1 | alphafold | PREDICTED | 59.43 | — |
Amino-acid sequence (694 residues)
MQPAIQVWFG EDLPLSPRSP LTPRHGPGLA NVCQYDEWIA VRHEATLLPM QEDLSIWLSG LLGIKVKAEK LLEELDNGVL LCQLIDVLQN MVKTCNSEES GNFPMRKVPC KKDAASGSFF ARDNTANFLH WCRDIGVDET YLFESEGLVL HKDPRQVYLC LLEIGRIVSR YGVEPPVLVK LEKEIELEET LLNTSGPEDS ISIPKSCCRH EELHEAVKHI AEDPPCSCSH RFSIEYLSEG RYRLGDKILF IRMLHGKHVM VRVGGGWDTL QGFLLKYDPC RILQFATLEQ KILAFQKGVS NESVPDSPAR TPQPPEMNPL SAVNMFQKQN SKPSVPVSIP KSKEKQGRPP GALVPASSLK GGNLGSMSVR SKLPNSPAAS SHPKLKSSKG ITKKPQAPSN NASSSLASLN PVGKNTSSPA LPRTAPCISE SPRKCISSPN TPKAKVIPAQ NSADLPESTL LPNKCSGKTQ PKYLKHNHIS SRDNAVSHLA AHSNSSSKCP KLPKANIPVR PKPSFQSSAK MTKTSSKTIA TGLGTQSQPS DGAPQAKPVP AQKLKSALNL NQPVSVSSVS PVKATQKSKD KNIVSATKKQ PQNKSAFQKT GPSSLKSPGR TPLSIVSLPQ SSTKTQTAPK SAQTVAKSQH STKGPPRSGK TPASIRKPPS SVKDADSGDK KPTAKKKEDD DHYFVMTGSK KPRK
Explore GAS2-like protein 3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets