Prostate tumor-overexpressed gene 1 protein (PTOV1)

About Prostate tumor-overexpressed gene 1 protein

Prostate tumor-overexpressed gene 1 protein (PTOV1) is a protein from Homo sapiens identified by UniProt accession Q86YD1, 416 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.

Target properties

Protein name	Prostate tumor-overexpressed gene 1 protein
UniProt accession	Q86YD1
Gene	PTOV1
Organism	Homo sapiens
Length	416 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (67)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.40
body mass index · score 0.34
lean body mass · score 0.30
age at menarche · score 0.15
fat body mass · score 0.15
hepatocellular carcinoma · score 0.08
neoplasm · score 0.08
non-small cell lung carcinoma · score 0.07
whole body water mass · score 0.07
base metabolic rate measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86YD1-F1	alphafold	PREDICTED	67.20	—

Amino-acid sequence (416 residues)

MVRPRRAPYR SGAGGPLGGR GRPPRPLVVR AVRSRSWPAS PRGPQPPRIR ARSAPPMEGA RVFGALGPIG PSSPGLTLGG LAVSEHRLSN KLLAWSGVLE WQEKRRPYSD STAKLKRTLP CQAYVNQGEN LETDQWPQKL IMQLIPQQLL TTLGPLFRNS QLAQFHFTNR DCDSLKGLCR IMGNGFAGCM LFPHISPCEV RVLMLLYSSK KKIFMGLIPY DQSGFVSAIR QVITTRKQAV GPGGVNSGPV QIVNNKFLAW SGVMEWQEPR PEPNSRSKRW LPSHVYVNQG EILRTEQWPR KLYMQLIPQQ LLTTLVPLFR NSRLVQFHFT KDLETLKSLC RIMDNGFAGC VHFSYKASCE IRVLMLLYSS EKKIFIGLIP HDQGNFVNGI RRVIANQQQV LQRNLEQEQQ QRGMGG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards