About Ankyrin repeat domain-containing protein 13B
Ankyrin repeat domain-containing protein 13B (ANKRD13B) is a protein
from Homo sapiens identified by UniProt accession
Q86YJ7, 626 residues long.
MolForge cross-references it against 0 known binders and
31 disease associations.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 13B |
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| UniProt accession | Q86YJ7 |
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| Gene | ANKRD13B |
|---|
| Organism | Homo sapiens |
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| Length | 626 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (31)
Diseases linked to this target (Open Targets).
- coronary artery disease · score 0.26
- brain measurement · score 0.24
- lymphocyte count · score 0.22
- body height · score 0.18
- fat body mass · score 0.18
- heel bone mineral density · score 0.15
- cortical thickness · score 0.12
- neuroimaging measurement · score 0.12
- brain volume measurement · score 0.10
- erythrocyte count · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86YJ7-F1 | alphafold | PREDICTED | 71.42 | — |
Amino-acid sequence (626 residues)
MIPANASARK GPEGKYPLHY LVWHNRHREL EKEVRAGQVD IEQLDPRGRT PLHLATTLGH LECARVLLAH GADVGRENRS GWTVLQEAVS TRDLELVQLV LRYRDYQRVV KRLAGIPVLL EKLRKAQDFY VEMKWEFTSW VPLVSKICPS DTYKVWKSGQ NLRVDTTLLG FDHMTWQRGN RSFVFRGQDT SAVVMEIDHD RRVVYTETLA LAGQDRELLL AAAQPTEEQV LSRLTAPVVT TQLDTKNISF ERNKTGILGW RSEKTEMVNG YEAKVYGASN VELITRTRTE HLSEQHKGKV KGCKTPLQSF LGIAEQHGGP QNGTLITQTL SQANPTAITA EEYFNPNFEL GNRDMGRPME LTTKTQKFKA KLWLCEEHPL SLCEQVAPII DLMAVSNALF AKLRDFITLR LPPGFPVKIE IPIFHILNAR ITFGNLNGCD EPVPSVRGSP SSETPSPGSD SSSVSSSSST TSCRGCEISP ALFEAPRGYS MMGGQREAAT RDDDDDLLQF AIQQSLLEAG SEYDQVTIWE ALTNSKPGTH PMSYEGRRQD RSAPPTPQRQ PAPPASVPSP RPSSGPGSGG HVFRSYDEQL RLAMELSAQE QEERRRRARQ EEEELERILR LSLTEQ
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