About Calcium/calmodulin-dependent protein kinase type 1D
Calcium/calmodulin-dependent protein kinase type 1D (CAMK1D) is a protein
from Homo sapiens identified by UniProt accession
Q8IU85, 385 residues long.
MolForge cross-references it against 0 known binders and
97 disease associations.
Target properties
| Protein name | Calcium/calmodulin-dependent protein kinase type 1D |
|---|
| UniProt accession | Q8IU85 |
|---|
| Gene | CAMK1D |
|---|
| Organism | Homo sapiens |
|---|
| Length | 385 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (11)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (97)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.43
- HbA1c measurement · score 0.39
- PHF-tau measurement · score 0.36
- sleep apnea · score 0.36
- mathematical ability · score 0.35
- insulin like growth factor measurement · score 0.34
- body height · score 0.32
- neuroinflammatory disorder · score 0.30
- schizophrenia · score 0.30
- intelligence · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IU85-F1 | alphafold | PREDICTED | 75.70 | — |
Amino-acid sequence (385 residues)
MARENGESSS SWKKQAEDIK KIFEFKETLG TGAFSEVVLA EEKATGKLFA VKCIPKKALK GKESSIENEI AVLRKIKHEN IVALEDIYES PNHLYLVMQL VSGGELFDRI VEKGFYTEKD ASTLIRQVLD AVYYLHRMGI VHRDLKPENL LYYSQDEESK IMISDFGLSK MEGKGDVMST ACGTPGYVAP EVLAQKPYSK AVDCWSIGVI AYILLCGYPP FYDENDSKLF EQILKAEYEF DSPYWDDISD SAKDFIRNLM EKDPNKRYTC EQAARHPWIA GDTALNKNIH ESVSAQIRKN FAKSKWRQAF NATAVVRHMR KLHLGSSLDS SNASVSSSLS LASQKDCLAP STLCSFISSS SGVSGVGAER RPRPTTVTAV HSGSK
Explore Calcium/calmodulin-dependent protein kinase type 1D with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets