Solute carrier family 41 member 1 (SLC41A1)

About Solute carrier family 41 member 1

Solute carrier family 41 member 1 (SLC41A1) is a protein from Homo sapiens identified by UniProt accession Q8IVJ1, 513 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.

Target properties

Protein name	Solute carrier family 41 member 1
UniProt accession	Q8IVJ1
Gene	SLC41A1
Organism	Homo sapiens
Length	513 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (71)

Diseases linked to this target (Open Targets).

monocyte count · score 0.39
nephronophthisis · score 0.34
platelet crit · score 0.28
monocyte percentage of leukocytes · score 0.28
cortical surface area measurement · score 0.27
cortical thickness · score 0.27
brain measurement · score 0.27
neuroimaging measurement · score 0.26
total blood protein measurement · score 0.26
IGF-1 measurement · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IVJ1-F1	alphafold	PREDICTED	77.85	—

Amino-acid sequence (513 residues)

MSSKPEPKDV HQLNGTGPSA SPCSSDGPGR EPLAGTSEFL GPDGAGVEVV IESRANAKGV REEDALLENG SQSNESDDVS TDRGPAPPSP LKETSFSIGL QVLFPFLLAG FGTVAAGMVL DIVQHWEVFQ KVTEVFILVP ALLGLKGNLE MTLASRLSTA ANIGHMDTPK ELWRMITGNM ALIQVQATVV GFLASIAAVV FGWIPDGHFS IPHAFLLCAS SVATAFIASL VLGMIMIGVI IGSRKIGINP DNVATPIAAS LGDLITLALL SGISWGLYLE LNHWRYIYPL VCAFFVALLP VWVVLARRSP ATREVLYSGW EPVIIAMAIS SVGGLILDKT VSDPNFAGMA VFTPVINGVG GNLVAVQASR ISTFLHMNGM PGENSEQAPR RCPSPCTTFF SPDVNSRSAR VLFLLVVPGH LVFLYTISCM QGGHTTLTLI FIIFYMTAAL LQVLILLYIA DWMVHWMWGR GLDPDNFSIP YLTALGDLLG TGLLALSFHV LWLIGDRDTD VGD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards