About Sperm acrosome developmental regulator
Sperm acrosome developmental regulator (SPACDR) is a protein
from Homo sapiens identified by UniProt accession
Q8IZ16, 206 residues long.
MolForge cross-references it against 0 known binders and
19 disease associations.
Target properties
| Protein name | Sperm acrosome developmental regulator |
|---|
| UniProt accession | Q8IZ16 |
|---|
| Gene | SPACDR |
|---|
| Organism | Homo sapiens |
|---|
| Length | 206 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (19)
Diseases linked to this target (Open Targets).
- platelet count · score 0.19
- self reported educational attainment · score 0.19
- platelet crit · score 0.16
- platelet component distribution width · score 0.15
- monocyte count · score 0.15
- heel bone mineral density · score 0.11
- blood protein measurement · score 0.07
- Red cell distribution width · score 0.07
- grip strength measurement · score 0.03
- serum albumin measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8IZ16-F1 | alphafold | PREDICTED | 60.07 | — |
Amino-acid sequence (206 residues)
MVVVMKFFRW VRRAWQRIIS WVFFWRQKIK PTISGHPDSK KHSLKKMEKT LQVVETLRLV ELPKEAKPKL GESPELADPC VLAKTTEETE VELGQQGQSL LQLPRTAVKS VSTLMVSALQ SGWQMCSWKS SVSSASVSSQ VRTQSPLKTP EAELLWEVYL VLWAVRKHLR RLYRRQERHR RHHVRCHAAP RPNPAQSLKL DAQSPL
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