Solute carrier family 38 member 6 (SLC38A6)

About Solute carrier family 38 member 6

Solute carrier family 38 member 6 (SLC38A6) is a protein from Homo sapiens identified by UniProt accession Q8IZM9, 456 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	Solute carrier family 38 member 6
UniProt accession	Q8IZM9
Gene	SLC38A6
Organism	Homo sapiens
Length	456 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

cortical surface area measurement · score 0.16
lip morphology measurement · score 0.14
optic cup area measurement · score 0.04
cytokine measurement · score 0.04
response to vaccine · score 0.04
vital capacity · score 0.03
Sepsis · score 0.03
type 2 diabetes mellitus · score 0.03
Abnormal urine sodium concentration · score 0.02
hepatocellular carcinoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8IZM9-F1	alphafold	PREDICTED	84.08	—

Amino-acid sequence (456 residues)

MEASWGSFNA ERGWYVSVQQ PEEAEAEELS PLLSNELHRQ RSPGVSFGLS VFNLMNAIMG SGILGLAYVL ANTGVFGFSF LLLTVALLAS YSVHLLLSMC IQTAVTSYED LGLFAFGLPG KLVVAGTIII QNIGAMSSYL LIIKTELPAA IAEFLTGDYS RYWYLDGQTL LIIICVGIVF PLALLPKIGF LGYTSSLSFF FMMFFALVVI IKKWSIPCPL TLNYVEKGFQ ISNVTDDCKP KLFHFSKESA YALPTMAFSF LCHTSILPIY CELQSPSKKR MQNVTNTAIA LSFLIYFISA LFGYLTFYDK VESELLKGYS KYLSHDVVVM TVKLCILFAV LLTVPLIHFP ARKAVTMMFF SNFPFSWIRH FLITLALNII IVLLAIYVPD IRNVFGVVGA STSTCLIFIF PGLFYLKLSR EDFLSWKKLG AFVLLIFGIL VGNFSLALII FDWINK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards