Protein SYS1 homolog (SYS1)

About Protein SYS1 homolog

Protein SYS1 homolog (SYS1) is a protein from Homo sapiens identified by UniProt accession Q8N2H4, 156 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Protein SYS1 homolog
UniProt accession	Q8N2H4
Gene	SYS1
Organism	Homo sapiens
Length	156 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
FEV/FVC ratio · score 0.02
Lipodystrophy · score 0.00
IGA glomerulonephritis · score 0.00
calf circumference measurement · score 0.00
Atrophy · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N2H4-F1	alphafold	PREDICTED	91.62	—

Amino-acid sequence (156 residues)

MAGQFRSYVW DPLLILSQIV LMQTVYYGSL GLWLALVDGL VRSSPSLDQM FDAEILGFST PPGRLSMMSF ILNALTCALG LLYFIRRGKQ CLDFTVTVHF FHLLGCWFYS SRFPSALTWW LVQAVCIALM AVIGEYLCMR TELKEIPLNS APKSNV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards