Fibrinogen C domain-containing protein 1 (FIBCD1)

About Fibrinogen C domain-containing protein 1

Fibrinogen C domain-containing protein 1 (FIBCD1) is a protein from Homo sapiens identified by UniProt accession Q8N539, 461 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.

Target properties

Protein name	Fibrinogen C domain-containing protein 1
UniProt accession	Q8N539
Gene	FIBCD1
Organism	Homo sapiens
Length	461 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (55)

Diseases linked to this target (Open Targets).

body mass index · score 0.38
body weight · score 0.28
body fat percentage · score 0.27
type 2 diabetes mellitus · score 0.25
insomnia measurement · score 0.25
body height · score 0.25
lean body mass · score 0.23
fat body mass · score 0.23
waist circumference · score 0.14
hepatocellular carcinoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N539-F1	alphafold	PREDICTED	80.08	—

Amino-acid sequence (461 residues)

MVNDRWKTMG GAAQLEDRPR DKPQRPSCGY VLCTVLLALA VLLAVAVTGA VLFLNHAHAP GTAPPPVVST GAASANSALV TVERADSSHL SILIDPRCPD LTDSFARLES AQASVLQALT EHQAQPRLVG DQEQELLDTL ADQLPRLLAR ASELQTECMG LRKGHGTLGQ GLSALQSEQG RLIQLLSESQ GHMAHLVNSV SDILDALQRD RGLGRPRNKA DLQRAPARGT RPRGCATGSR PRDCLDVLLS GQQDDGVYSV FPTHYPAGFQ VYCDMRTDGG GWTVFQRRED GSVNFFRGWD AYRDGFGRLT GEHWLGLKRI HALTTQAAYE LHVDLEDFEN GTAYARYGSF GVGLFSVDPE EDGYPLTVAD YSGTAGDSLL KHSGMRFTTK DRDSDHSENN CAAFYRGAWW YRNCHTSNLN GQYLRGAHAS YADGVEWSSW TGWQYSLKFS EMKIRPVRED R

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards