PRELI domain-containing protein 2 (PRELID2)

About PRELI domain-containing protein 2

PRELI domain-containing protein 2 (PRELID2) is a protein from Homo sapiens identified by UniProt accession Q8N945, 189 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	PRELI domain-containing protein 2
UniProt accession	Q8N945
Gene	PRELID2
Organism	Homo sapiens
Length	189 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

protein measurement · score 0.34
smoking status measurement · score 0.29
vitamin B12 measurement · score 0.29
mathematical ability · score 0.24
age at onset · score 0.23
Alzheimer disease · score 0.23
body mass index · score 0.23
triglyceride measurement · score 0.20
lymphocyte count · score 0.20
hepatocellular carcinoma · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N945-F1	alphafold	PREDICTED	87.04	—

Amino-acid sequence (189 residues)

MGVSVDVHQV YKYPFEQVVA SFLRKYPNPM DKNVISVKIM EEKRDESTGV IYRKRIAICQ NVVPEILRKS LSTLVILCWK KVSILKVPNI QLEEESWLNP RERNMAIRSH CLTWTQYASM KEESVFRESM ENPNWTEFIQ RGRISITGVG FLNCVLETFA STFLRQGAQK GIRIMEMLLK EQCGAPLAE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards