About Zinc finger protein 709
Zinc finger protein 709 (ZNF709) is a protein
from Homo sapiens identified by UniProt accession
Q8N972, 641 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Zinc finger protein 709 |
| UniProt accession | Q8N972 |
| Gene | ZNF709 |
| Organism | Homo sapiens |
| Length | 641 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- cognitive function measurement · score 0.17
- type 2 diabetes mellitus · score 0.14
- self reported educational attainment · score 0.13
- erythrocyte count · score 0.09
- mathematical ability · score 0.07
- hemoglobin measurement · score 0.07
- hypertension · score 0.04
- diastolic blood pressure · score 0.04
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q8N972-F1 | alphafold | PREDICTED | 80.53 | — |
Amino-acid sequence (641 residues)
MDSVVFEDVA VNFTQEEWAL LGPSQKKLYR DVMQETFVNL ASIGENWEEK NIEDHKNQGR KLRSHMVERL CERKEGSQFG ETISQTPNPK PNKKTFTRVK PYECSVCGKD YMCHSSLNRH MRSHTEHRSY EYHKYGEKSY ECKECGKRFS FRSSFRIHER THTGEKPYKC KQCGKAFSWP SSFQIHERTH TGEKPYECKE CGKAFIYHTT FRGHMRMHTG EKPYKCKECG KTFSHPSSFR NHERTHSGEK PYECKQCGKA FRYYQTFQIH ERTHTGEKPY QCKQCGKALS CPTSFRSHER IHTGEKPYKC KKCGKAFSFP SSFRKHERIH TGEKPYDCKE CGKAFISLPS YRRHMIMHTG NGPYKCKECG KAFDCPSSFQ IHERTHTGEK PYECKQCGKA FSCSSSFRMH ERTHTGEKPH ECKQCGKAFS CSSSVRIHER THTGEKPYEC KQCGKAFSCS SSFRMHERIH TGEKPYECKQ CGKAFSFSSS FRMHERTHTG EKPYECKQCG KAFSCSSSFR MHERTHTGEK PYECKQCGKA FSCSSSIRIH ERTHTGEKPY ECKQCGKAFS CSSSVRMHER THTGVKPYEC KQCDKAFSCS RSFRIHERTH TGEKPYACQQ CGKAFKCSRS FRIHERVHSG E
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