Lysophospholipase D GDPD1 (GDPD1)

About Lysophospholipase D GDPD1

Lysophospholipase D GDPD1 (GDPD1) is a protein from Homo sapiens identified by UniProt accession Q8N9F7, 314 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

Target properties

Protein name	Lysophospholipase D GDPD1
UniProt accession	Q8N9F7
Gene	GDPD1
Organism	Homo sapiens
Length	314 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (24)

Diseases linked to this target (Open Targets).

leukocyte count · score 0.33
breast adenocarcinoma · score 0.23
myeloid white cell count · score 0.20
type 1 diabetes mellitus · score 0.16
protein measurement · score 0.13
mean corpuscular hemoglobin concentration · score 0.12
head and neck squamous cell carcinoma · score 0.11
platelet count · score 0.11
systolic blood pressure · score 0.08
diastolic blood pressure · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N9F7-F1	alphafold	PREDICTED	96.04	—

Amino-acid sequence (314 residues)

MSSTAAFYLL STLGGYLVTS FLLLKYPTLL HQRKKQRFLS KHISHRGGAG ENLENTMAAF QHAVKIGTDM LELDCHITKD EQVVVSHDEN LKRATGVNVN ISDLKYCELP PYLGKLDVSF QRACQCEGKD NRIPLLKEVF EAFPNTPINI DIKVNNNVLI KKVSELVKRY NREHLTVWGN ANYEIVEKCY KENSDIPILF SLQRVLLILG LFFTGLLPFV PIREQFFEIP MPSIILKLKE PHTMSRSQKF LIWLSDLLLM RKALFDHLTA RGIQVYIWVL NEEQEYKRAF DLGATGVMTD YPTKLRDFLH NFSA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards