Protein APCDD1-like (APCDD1L)

About Protein APCDD1-like

Protein APCDD1-like (APCDD1L) is a protein from Homo sapiens identified by UniProt accession Q8NCL9, 501 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein name	Protein APCDD1-like
UniProt accession	Q8NCL9
Gene	APCDD1L
Organism	Homo sapiens
Length	501 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (33)

Diseases linked to this target (Open Targets).

nonpapillary renal cell carcinoma · score 0.08
non-small cell lung carcinoma · score 0.05
visual perception measurement · score 0.05
central nervous system cancer · score 0.05
wet macular degeneration · score 0.04
atrophic macular degeneration · score 0.04
age-related macular degeneration · score 0.04
platelet component distribution width · score 0.03
mean platelet volume · score 0.03
oral squamous cell carcinoma · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NCL9-F1	alphafold	PREDICTED	81.59	—

Amino-acid sequence (501 residues)

MPAAMLPYAC VLVLLGAHTA PAAGEAGGSC LRWEPHCQQP LPDRVPSTAI LPPRLNGPWI STGCEVRPGP EFLTRAYTFY PSRLFRAHQF YYEDPFCGEP AHSLLVKGKV RLRRASWVTR GATEADYHLH KVGIVFHSRR ALVDVTGRLN QTRAGRDCAR RLPPARAWLP GALYELRSAR AQGDCLEALG LTMHELSLVR VQRRLQPQPR ASPRLVEELY LGDIHTDPAE RRHYRPTGYQ RPLQSALHHV QPCPACGLIA RSDVHHPPVL PPPLALPLHL GGWWVSSGCE VRPAVLFLTR LFTFHGHSRS WEGYYHHFSD PACRQPTFTV YAAGRYTRGT PSTRVRGGTE LVFEVTRAHV TPMDQVTTAM LNFSEPSSCG GAGAWSMGTE RDVTATNGCL PLGIRLPHVE YELFKMEQDP LGQSLLFIGQ RPTDGSSPDT PEKRPTSYQA PLVLCHGEAP DFSRPPQHRP SLQKHPSTGG LHIAPFPLLP LVLGLAFLHW L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards