About Olfactory receptor 5AP2
Olfactory receptor 5AP2 (OR5AP2) is a protein
from Homo sapiens identified by UniProt accession
Q8NGF4, 316 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Olfactory receptor 5AP2 |
|---|
| UniProt accession | Q8NGF4 |
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| Gene | OR5AP2 |
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| Organism | Homo sapiens |
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| Length | 316 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- glucose measurement · score 0.25
- neuroblastoma · score 0.21
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- clear cell renal carcinoma · score 0.18
- hepatocellular carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- intraocular pressure measurement · score 0.15
- pancreatic adenocarcinoma · score 0.04
- systolic blood pressure · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGF4-F1 | alphafold | PREDICTED | 88.32 | — |
Amino-acid sequence (316 residues)
MRLMKEVRGR NQTEVTEFLL LGLSDNPDLQ GVLFALFLLI YMANMVGNLG MIVLIKIDLC LHTPMYFFLS SLSFVDASYS SSVTPKMLVN LMAENKAISF HGCAAQFYFF GSFLGTECFL LAMMAYDRYA AIWNPLLYPV LVSGRICFLL IATSFLAGCG NAAIHTGMTF RLSFCGSNRI NHFYCDTPPL LKLSCSDTHF NGIVIMAFSS FIVISCVMIV LISYLCIFIA VLKMPSLEGR HKAFSTCASY LMAVTIFFGT ILFMYLRPTS SYSMEQDKVV SVFYTVIIPV LNPLIYSLKN KDVKKALKKI LWKHIL
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