About Olfactory receptor 5A1
Olfactory receptor 5A1 (OR5A1) is a protein
from Homo sapiens identified by UniProt accession
Q8NGJ0, 315 residues long.
MolForge cross-references it against 0 known binders and
10 disease associations.
Target properties
| Protein name | Olfactory receptor 5A1 |
|---|
| UniProt accession | Q8NGJ0 |
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| Gene | OR5A1 |
|---|
| Organism | Homo sapiens |
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| Length | 315 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (10)
Diseases linked to this target (Open Targets).
- smoking behavior · score 0.32
- smoking status measurement · score 0.25
- sensory perception of smell · score 0.23
- low grade glioma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- body height · score 0.03
- breast carcinoma · score 0.02
- gastric carcinoma · score 0.00
- papillary thyroid carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGJ0-F1 | alphafold | PREDICTED | 88.16 | — |
Amino-acid sequence (315 residues)
MSITKAWNSS SVTMFILLGF TDHPELQALL FVTFLGIYLT TLAWNLALIF LIRGDTHLHT PMYFFLSNLS FIDICYSSAV APNMLTDFFW EQKTISFVGC AAQFFFFVGM GLSECLLLTA MAYDRYAAIS SPLLYPTIMT QGLCTRMVVG AYVGGFLSSL IQASSIFRLH FCGPNIINHF FCDLPPVLAL SCSDTFLSQV VNFLVVVTVG GTSFLQLLIS YGYIVSAVLK IPSAEGRWKA CNTCASHLMV VTLLFGTALF VYLRPSSSYL LGRDKVVSVF YSLVIPMLNP LIYSLRNKEI KDALWKVLER KKVFS
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