Olfactory receptor 4C15 (OR4C15)

About Olfactory receptor 4C15

Olfactory receptor 4C15 (OR4C15) is a protein from Homo sapiens identified by UniProt accession Q8NGM1, 316 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Olfactory receptor 4C15
UniProt accession	Q8NGM1
Gene	OR4C15
Organism	Homo sapiens
Length	316 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

aspartate aminotransferase measurement · score 0.26
eosinophil count · score 0.24
glomerular filtration rate · score 0.20
clear cell renal carcinoma · score 0.18
chronic lymphocytic leukemia · score 0.18
ovarian cancer · score 0.18
breast adenocarcinoma · score 0.18
creatinine measurement · score 0.16
serum alanine aminotransferase measurement · score 0.16
acute myeloid leukemia · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGM1-F1	alphafold	PREDICTED	90.21	—

Amino-acid sequence (316 residues)

MQNQSFVTEF VLLGLSQNPN VQEIVFVVFL FVYIATVGGN MLIVVTILSS PALLVSPMYF FLGFLSFLDA CFSSVITPKM IVDSLYVTKT ISFEGCMMQL FAEHFFAGVE VIVLTAMAYD RYVAICKPLH YSSIMNRRLC GILMGVAWTG GLLHSMIQIL FTFQLPFCGP NVINHFMCDL YPLLELACTD THIFGLMVVI NSGFICIINF SLLLVSYAVI LLSLRTHSSE GRWKALSTCG SHIAVVILFF VPCIFVYTRP PSAFSLDKMA AIFYIILNPL LNPLIYTFRN KEVKQAMRRI WNRLMVVSDE KENIKL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards