About Olfactory receptor 10G4
Olfactory receptor 10G4 (OR10G4) is a protein
from Homo sapiens identified by UniProt accession
Q8NGN3, 311 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Olfactory receptor 10G4 |
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| UniProt accession | Q8NGN3 |
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| Gene | OR10G4 |
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| Organism | Homo sapiens |
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| Length | 311 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (7)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- clear cell renal carcinoma · score 0.18
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- chronic lymphocytic leukemia · score 0.18
- breast adenocarcinoma · score 0.18
- gastric carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGN3-F1 | alphafold | PREDICTED | 87.87 | — |
Amino-acid sequence (311 residues)
MSNASLVTAF ILTGLPHAPG LDALLFGIFL VVYVLTVLGN LLILLVIRVD SHLHTPMYYF LTNLSFIDMW FSTVTVPKML MTLVSPSGRA ISFHSCVAQL YFFHFLGSTE CFLYTVMSYD RYLAISYPLR YTSMMSGSRC ALLATGTWLS GSLHSAVQTI LTFHLPYCGP NQIQHYFCDA PPILKLACAD TSANVMVIFV DIGIVASGCF VLIVLSYVSI VCSILRIRTS DGRRRAFQTC ASHCIVVLCF FVPCVVIYLR PGSMDAMDGV VAIFYTVLTP LLNPVVYTLR NKEVKKAVLK LRDKVAHPQR K
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