About Olfactory receptor 5M9
Olfactory receptor 5M9 (OR5M9) is a protein
from Homo sapiens identified by UniProt accession
Q8NGP3, 310 residues long.
MolForge cross-references it against 0 known binders and
10 disease associations.
Target properties
| Protein name | Olfactory receptor 5M9 |
|---|
| UniProt accession | Q8NGP3 |
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| Gene | OR5M9 |
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| Organism | Homo sapiens |
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| Length | 310 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
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Disease associations (10)
Diseases linked to this target (Open Targets).
- chronic lymphocytic leukemia · score 0.18
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- blood pressure · score 0.06
- systolic blood pressure · score 0.03
- high density lipoprotein cholesterol measurement · score 0.02
- leukocyte count · score 0.02
- hypertrophic cardiomyopathy · score 0.02
- hypertension · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGP3-F1 | alphafold | PREDICTED | 89.86 | — |
Amino-acid sequence (310 residues)
MPNFTDVTEF TLLGLTCRQE LQVLFFVVFL AVYMITLLGN IGMIILISIS PQLQSPMYFF LSHLSFADVC FSSNVTPKML ENLLSETKTI SYVGCLVQCY FFIAVVHVEV YILAVMAFDR YMAGCNPLLY GSKMSRTVCV RLISVPYVYG FSVSLICTLW TYGLYFCGNF EINHFYCADP PLIQIACGRV HIKEITMIVI AGINFTYSLS VVLISYTLIV VAVLRMRSAD GRRKAFSTCG SHLTAVSMFY GTPIFMYLRR PTEESVEQGK MVAVFYTTVI PMLNPMIYSL RNKDVKEAVN KAITKTYVRQ
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