Olfactory receptor 1B1 (OR1B1)

About Olfactory receptor 1B1

Olfactory receptor 1B1 (OR1B1) is a protein from Homo sapiens identified by UniProt accession Q8NGR6, 317 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Olfactory receptor 1B1
UniProt accession	Q8NGR6
Gene	OR1B1
Organism	Homo sapiens
Length	317 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

clear cell renal carcinoma · score 0.18
breast adenocarcinoma · score 0.18
lymphocyte percentage of leukocytes · score 0.03
adenoma · score 0.02
cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGR6-F1	alphafold	PREDICTED	87.76	—

Amino-acid sequence (317 residues)

MSFAPNASHS PVFLLLGFSR ANISYTLLFF LFLAIYLTTI LGNVTLVLLI SWDSRLHSPM YYLLRGLSVI DMGLSTVTLP QLLAHLVSHY PTIPAARCLA QFFFFYAFGV TDTLVIAVMA LDRYVAICDP LHYALVMNHQ RCACLLALSW VVSILHTMLR VGLVLPLCWT GDAGGNVNLP HFFCDHRPLL RASCSDIHSN ELAIFFEGGF LMLGPCALIV LSYVRIGAAI LRLPSAAGRR RAVSTCGSHL TMVGFLYGTI ICVYFQPPFQ NSQYQDMVAS VMYTAITPLA NPFVYSLHNK DVKGALCRLL EWVKVDP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards