Olfactory receptor 1J4 (OR1J4)

About Olfactory receptor 1J4

Olfactory receptor 1J4 (OR1J4) is a protein from Homo sapiens identified by UniProt accession Q8NGS1, 313 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Olfactory receptor 1J4
UniProt accession	Q8NGS1
Gene	OR1J4
Organism	Homo sapiens
Length	313 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

breast adenocarcinoma · score 0.18
multiple myeloma · score 0.16
lymphocyte percentage of leukocytes · score 0.03
Crohn's disease · score 0.01
small cell lung carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGS1-F1	alphafold	PREDICTED	87.43	—

Amino-acid sequence (313 residues)

MKRENQSSVS EFLLLDLPIW PEQQAVFFTL FLGMYLITVL GNLLIILLIR LDSHLHTPMF FFLSHLALTD ISLSSVTVPK MLLSMQTQDQ SILYAGCVTQ MYFFIFFTDL DNFLLTSMAY DRYVAICHPL RYTTIMKEGL CNLLVTVSWI LSCTNALSHT LLLAQLSFCA DNTIPHFFCD LVALLKLSCS DISLNELVIF TVGQAVITLP LICILISYGH IGVTILKAPS TKGIFKALST CGSHLSVVSL YYGTIIGLYF LPSSSASSDK DVIASVMYTV ITPLLNPFIY SLRNRDIKGA LERLFNRATV LSQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards