Olfactory receptor 2K2 (OR2K2)

About Olfactory receptor 2K2

Olfactory receptor 2K2 (OR2K2) is a protein from Homo sapiens identified by UniProt accession Q8NGT1, 316 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein name	Olfactory receptor 2K2
UniProt accession	Q8NGT1
Gene	OR2K2
Organism	Homo sapiens
Length	316 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (33)

Diseases linked to this target (Open Targets).

monocyte count · score 0.40
monocyte percentage of leukocytes · score 0.36
neurodegenerative disease · score 0.27
granulocyte percentage of myeloid white cells · score 0.26
apolipoprotein A 1 measurement · score 0.25
age at menarche · score 0.23
BMI-adjusted waist-hip ratio · score 0.22
BMI-adjusted hip circumference · score 0.21
basophil count · score 0.20
erythrocyte count · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGT1-F1	alphafold	PREDICTED	87.09	—

Amino-acid sequence (316 residues)

MQGENFTIWS IFFLEGFSQY PGLEVVLFVF SLVMYLTTLL GNSTLILITI LDSRLKTPMY LFLGNLSFMD ICYTSASVPT LLVNLLSSQK TIIFSGCAVQ MYLSLAMGST ECVLLAVMAY DRYVAICNPL RYSIIMNRCV CARMATVSWV TGCLTALLET SFALQIPLCG NLIDHFTCEI LAVLKLACTS SLLMNTIMLV VSILLLPIPM LLVCISYIFI LSTILRITSA EGRNKAFSTC GAHLTVVILY YGAALSMYLK PSSSNAQKID KIISLLYGVL TPMLNPIIYS LRNKEVKDAM KKLLGKITLH QTHEHL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards