About Olfactory receptor 6Y1
Olfactory receptor 6Y1 (OR6Y1) is a protein
from Homo sapiens identified by UniProt accession
Q8NGX8, 325 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Olfactory receptor 6Y1 |
|---|
| UniProt accession | Q8NGX8 |
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| Gene | OR6Y1 |
|---|
| Organism | Homo sapiens |
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| Length | 325 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.28
- reticulocyte count · score 0.21
- ovarian cancer · score 0.18
- hepatocellular carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- mean corpuscular volume · score 0.16
- multiple myeloma · score 0.16
- Red cell distribution width · score 0.16
- mean reticulocyte volume · score 0.15
- total cholesterol measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGX8-F1 | alphafold | PREDICTED | 86.17 | — |
Amino-acid sequence (325 residues)
MTTIILEVDN HTVTTRFILL GFPTRPAFQL LFFSIFLATY LLTLLENLLI ILAIHSDGQL HKPMYFFLSH LSFLEMWYVT VISPKMLVDF LSHDKSISFN GCMTQLYFFV TFVCTEYILL AIMAFDRYVA ICNPLRYPVI MTNQLCGTLA GGCWFCGLMT AMIKMVFIAQ LHYCGMPQIN HYFCDISPLL NVSCEDASQA EMVDFFLALM VIAIPLCVVV ASYAAILATI LRIPSAQGRQ KAFSTCASHL TVVILFYSMT LFTYARPKLM YAYNSNKVVS VLYTVIVPLL NPIIYCLRNH EVKAALRKTI HCRGSGPQGN GAFSS
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