About Zinc finger protein 563
Zinc finger protein 563 (ZNF563) is a protein
from Homo sapiens identified by UniProt accession
Q8TA94, 476 residues long.
MolForge cross-references it against 0 known binders and
4 disease associations.
Target properties
| Protein name | Zinc finger protein 563 |
|---|
| UniProt accession | Q8TA94 |
|---|
| Gene | ZNF563 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 476 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (4)
Diseases linked to this target (Open Targets).
- bilirubin measurement · score 0.50
- Down syndrome · score 0.04
- mean corpuscular volume · score 0.04
- skin disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TA94-F1 | alphafold | PREDICTED | 70.22 | — |
Amino-acid sequence (476 residues)
MDAVAFEDVA VNFTQEEWAL LGPSQKNLYR YVMQETIRNL DCIRMIWEEQ NTEDQYKNPR RNLRCHMVER FSESKDSSQC GETFSLIRDS IVNNSICPGE DPCQSAECEE VIMGHLSLNS HIRVDSGHKP HEYQEYGEKP HTHKQRGKAF SYHHSFQSRG RPHTGKKRYE CKECGKTFSS RRNLRRHMVV QGGNRPYKCK LCGKAFFWPS LLRMHERTHT GEKPYECKQC SKAFPFYSSY RRHERMHTGE KPYECKQCSK ALPDSSSYIR HERTHTGEKP YTCKQCGKAF SVSSSLRRHE TTHSAEKPYE CKQCGKTFHH LGSFQIHMKR HTGDRPHKCK ICGKGFDRPS LVRYHERIHT GEKPYECKQC GKTLSHSSSF RRHMIMHTGG GPHKCKICGK AFVYPSVCQR HEKSHSGEKP YECKQCGKAL SHSSSFRRHM VMHTGDGPNK CKVCGKAFVY PSVCQRHEKT HWRETI
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