About Stomatin-like protein 3
Stomatin-like protein 3 (STOML3) is a protein
from Homo sapiens identified by UniProt accession
Q8TAV4, 291 residues long.
MolForge cross-references it against 0 known binders and
36 disease associations.
Target properties
| Protein name | Stomatin-like protein 3 |
|---|
| UniProt accession | Q8TAV4 |
|---|
| Gene | STOML3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 291 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (36)
Diseases linked to this target (Open Targets).
- body height · score 0.28
- breast adenocarcinoma · score 0.16
- head and neck squamous cell carcinoma · score 0.12
- FEV/FVC ratio · score 0.09
- adolescent idiopathic scoliosis · score 0.06
- central nervous system cancer · score 0.03
- psoriasis · score 0.02
- neoplasm · score 0.01
- gliosarcoma · score 0.01
- Bardet-Biedl syndrome · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TAV4-F1 | alphafold | PREDICTED | 84.33 | — |
Amino-acid sequence (291 residues)
MDSRVSSPEK QDKENFVGVN NKRLGVCGWI LFSLSFLLVI ITFPISIWMC LKIIKEYERA VVFRLGRIQA DKAKGPGLIL VLPCIDVFVK VDLRTVTCNI PPQEILTRDS VTTQVDGVVY YRIYSAVSAV ANVNDVHQAT FLLAQTTLRN VLGTQTLSQI LAGREEIAHS IQTLLDDATE LWGIRVARVE IKDVRIPVQL QRSMAAEAEA TREARAKVLA AEGEMNASKS LKSASMVLAE SPIALQLRYL QTLSTVATEK NSTIVFPLPM NILEGIGGVS YDNHKKLPNK A
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