About N-acylneuraminate-9-phosphatase
N-acylneuraminate-9-phosphatase (NANP) is a protein
from Homo sapiens identified by UniProt accession
Q8TBE9, 248 residues long.
MolForge cross-references it against 0 known binders and
76 disease associations.
Target properties
| Protein name | N-acylneuraminate-9-phosphatase |
|---|
| UniProt accession | Q8TBE9 |
|---|
| Gene | NANP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 248 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (76)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.10
- forced expiratory volume · score 0.09
- mean corpuscular volume · score 0.09
- diet measurement · score 0.06
- body fat percentage · score 0.05
- lean body mass · score 0.05
- fat body mass · score 0.04
- age at menopause · score 0.04
- serum alanine aminotransferase measurement · score 0.04
- lymphocyte count · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TBE9-F1 | alphafold | PREDICTED | 94.77 | — |
Amino-acid sequence (248 residues)
MGLSRVRAVF FDLDNTLIDT AGASRRGMLE VIKLLQSKYH YKEEAEIICD KVQVKLSKEC FHPYNTCITD LRTSHWEEAI QETKGGAANR KLAEECYFLW KSTRLQHMTL AEDVKAMLTE LRKEVRLLLL TNGDRQTQRE KIEACACQSY FDAVVVGGEQ REEKPAPSIF YYCCNLLGVQ PGDCVMVGDT LETDIQGGLN AGLKATVWIN KNGIVPLKSS PVPHYMVSSV LELPALLQSI DCKVSMST
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