About Calmodulin-like protein 6
Calmodulin-like protein 6 (CALML6) is a protein
from Homo sapiens identified by UniProt accession
Q8TD86, 181 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Calmodulin-like protein 6 |
| UniProt accession | Q8TD86 |
| Gene | CALML6 |
| Organism | Homo sapiens |
| Length | 181 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.28
- body mass index · score 0.19
- hemoglobin measurement · score 0.10
- blood protein measurement · score 0.09
- body weight · score 0.06
- lean body mass · score 0.05
- electrocardiography · score 0.05
- lifestyle measurement · score 0.05
- waist circumference · score 0.05
- mean corpuscular hemoglobin concentration · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q8TD86-F1 | alphafold | PREDICTED | 78.35 | — |
Amino-acid sequence (181 residues)
MGLQQEISLQ PWCHHPAESC QTTTDMTERL SAEQIKEYKG VFEMFDEEGN GEVKTGELEW LMSLLGINPT KSELASMAKD VDRDNKGFFN CDGFLALMGV YHEKAQNQES ELRAAFRVFD KEGKGYIDWN TLKYVLMNAG EPLNEVEAEQ MMKEADKDGD RTIDYEEFVA MMTGESFKLI Q
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