Calmodulin-like protein 6 (CALML6)

Homo sapiens — UniProt Q8TD86

Gene: CALML6Homo sapiensSwissProt reviewed

About Calmodulin-like protein 6

Calmodulin-like protein 6 (CALML6) is a protein from Homo sapiens identified by UniProt accession Q8TD86, 181 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein nameCalmodulin-like protein 6
UniProt accessionQ8TD86
GeneCALML6
OrganismHomo sapiens
Length181 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (29)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.28
  • body mass index · score 0.19
  • hemoglobin measurement · score 0.10
  • blood protein measurement · score 0.09
  • body weight · score 0.06
  • lean body mass · score 0.05
  • electrocardiography · score 0.05
  • lifestyle measurement · score 0.05
  • waist circumference · score 0.05
  • mean corpuscular hemoglobin concentration · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8TD86-F1alphafoldPREDICTED78.35—

Amino-acid sequence (181 residues)

MGLQQEISLQ PWCHHPAESC QTTTDMTERL SAEQIKEYKG VFEMFDEEGN GEVKTGELEW LMSLLGINPT KSELASMAKD VDRDNKGFFN CDGFLALMGV YHEKAQNQES ELRAAFRVFD KEGKGYIDWN TLKYVLMNAG EPLNEVEAEQ MMKEADKDGD RTIDYEEFVA MMTGESFKLI Q

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Quick facts

UniProtQ8TD86
GeneCALML6
OrganismHomo sapiens
Length181
Binders0
Diseases29
View on UniProt