About Suppressor of tumorigenicity 7 protein-like
Suppressor of tumorigenicity 7 protein-like (ST7L) is a protein
from Homo sapiens identified by UniProt accession
Q8TDW4, 575 residues long.
MolForge cross-references it against 0 known binders and
72 disease associations.
Target properties
| Protein name | Suppressor of tumorigenicity 7 protein-like |
|---|
| UniProt accession | Q8TDW4 |
|---|
| Gene | ST7L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 575 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (72)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.44
- mean platelet volume · score 0.42
- systolic blood pressure · score 0.39
- brain measurement · score 0.37
- neurodegenerative disease · score 0.37
- platelet count · score 0.36
- neuroimaging measurement · score 0.35
- platelet component distribution width · score 0.34
- cortical surface area measurement · score 0.34
- platelet crit · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TDW4-F1 | alphafold | PREDICTED | 79.19 | — |
Amino-acid sequence (575 residues)
MADRGGVGEA AAVGASPASV PGLNPTLGWR ERLRAGLAGT GASLWFVAGL GLLYALRIPL RLCENLAAVT VFLNSLTPKF YVALTGTSSL ISGLIFIFEW WYFHKHGTSF IEQVSVSHLQ PLMGGTESSI SEPGSPSRNR ENETSRQNLS ECKVWRNPLN LFRGAEYRRY TWVTGKEPLT YYDMNLSAQD HQTFFTCDTD FLRPSDTVMQ KAWRERNPPA RIKAAYQALE LNNDCATAYV LLAEEEATTI VDAERLFKQA LKAGETIYRQ SQQCQHQSPQ HEAQLRRDTN VLVYIKRRLA MCARKLGRIR EAVKIMRDLM KEFPPLTMLN IHENLLESLL ELQAYPDVQA VLAKYDDISL PKSAAICYTA ALLKTRTVSE KFSPETASRR GLSTAEINAV EAIHRAVEFN PHVPKYLLEM KSLILPPEHI LKRGDSEAIA YAFFHLQHWK RIEGALNLLQ CTWEGTFRMI PYPLEKGHLF YPYPSCTETA DRELLPTFHH VSVYPKKELP LFIHFTAGFC SSTAMIAILT HQFPEIMGIF AKAVLGLWCP QPWASSGFEE NTQDLKSEDL GLSSG
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