About Anion exchange transporter
Anion exchange transporter (SLC26A7) is a protein
from Homo sapiens identified by UniProt accession
Q8TE54, 656 residues long.
MolForge cross-references it against 0 known binders and
100 disease associations.
Target properties
| Protein name | Anion exchange transporter |
|---|
| UniProt accession | Q8TE54 |
|---|
| Gene | SLC26A7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 656 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (100)
Diseases linked to this target (Open Targets).
- pulse pressure measurement · score 0.36
- body height · score 0.32
- intraocular pressure measurement · score 0.32
- congenital hypothyroidism · score 0.28
- type 1 diabetes mellitus · score 0.25
- genetic disorder · score 0.19
- appendicular lean mass · score 0.17
- cortical surface area measurement · score 0.17
- sitting height measurement · score 0.17
- cutaneous melanoma · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TE54-F1 | alphafold | PREDICTED | 80.89 | — |
Amino-acid sequence (656 residues)
MTGAKRKKKS MLWSKMHTPQ CEDIIQWCRR RLPILDWAPH YNLKENLLPD TVSGIMLAVQ QVTQGLAFAV LSSVHPVFGL YGSLFPAIIY AIFGMGHHVA TGTFALTSLI SANAVERIVP QNMQNLTTQS NTSVLGLSDF EMQRIHVAAA VSFLGGVIQV AMFVLQLGSA TFVVTEPVIS AMTTGAATHV VTSQVKYLLG MKMPYISGPL GFFYIYAYVF ENIKSVRLEA LLLSLLSIVV LVLVKELNEQ FKRKIKVVLP VDLVLIIAAS FACYCTNMEN TYGLEVVGHI PQGIPSPRAP PMNILSAVIT EAFGVALVGY VASLALAQGS AKKFKYSIDD NQEFLAHGLS NIVSSFFFCI PSAAAMGRTA GLYSTGAKTQ VACLISCIFV LIVIYAIGPL LYWLPMCVLA SIIVVGLKGM LIQFRDLKKY WNVDKIDWGI WVSTYVFTIC FAANVGLLFG VVCTIAIVIG RFPRAMTVSI KNMKEMEFKV KTEMDSETLQ QVKIISINNP LVFLNAKKFY TDLMNMIQKE NACNQPLDDI SKCEQNTLLN SLSNGNCNEE ASQSCPNEKC YLILDCSGFT FFDYSGVSML VEVYMDCKGR SVDVLLAHCT ASLIKAMTYY GNLDSEKPIF FESVSAAISH IHSNKNLSKL SDHSEV
Explore Anion exchange transporter with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets