Dual specificity protein phosphatase 19 (DUSP19)

About Dual specificity protein phosphatase 19

Dual specificity protein phosphatase 19 (DUSP19) is a protein from Homo sapiens identified by UniProt accession Q8WTR2, 217 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	Dual specificity protein phosphatase 19
UniProt accession	Q8WTR2
Gene	DUSP19
Organism	Homo sapiens
Length	217 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.32
social interaction measurement · score 0.18
muscular dystrophy · score 0.16
Abnormality of refraction · score 0.15
traffic air pollution measurement · score 0.11
platelet component distribution width · score 0.07
age at first sexual intercourse measurement · score 0.07
attention deficit hyperactivity disorder · score 0.06
substance abuse · score 0.06
antisocial behaviour measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WTR2-F1	alphafold	PREDICTED	88.20	—

Amino-acid sequence (217 residues)

MYSLNQEIKA FSRNNLRKQC TRVTTLTGKK IIETWKDARI HVVEEVEPSS GGGCGYVQDL SSDLQVGVIK PWLLLGSQDA AHDLDTLKKN KVTHILNVAY GVENAFLSDF TYKSISILDL PETNILSYFP ECFEFIEEAK RKDGVVLVHC NAGVSRAAAI VIGFLMNSEQ TSFTSAFSLV KNARPSICPN SGFMEQLRTY QEGKESNKCD RIQENSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards