About Scavenger receptor cysteine-rich domain-containing group B protein
Scavenger receptor cysteine-rich domain-containing group B protein (SSC4D) is a protein
from Homo sapiens identified by UniProt accession
Q8WTU2, 575 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Scavenger receptor cysteine-rich domain-containing group B protein |
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| UniProt accession | Q8WTU2 |
|---|
| Gene | SSC4D |
|---|
| Organism | Homo sapiens |
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| Length | 575 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (9)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.27
- triglyceride measurement · score 0.25
- osteoarthritis · score 0.07
- drug use measurement · score 0.05
- metabolite measurement · score 0.02
- chronic kidney disease · score 0.01
- juvenile dermatomyositis · score 0.01
- glioblastoma multiforme · score 0.00
- Sepsis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WTU2-F1 | alphafold | PREDICTED | 73.57 | — |
Amino-acid sequence (575 residues)
MHKEAEMLIG PQLDEKRWGW RLGDGSAAPP FLPQALSFLL LLPLASALQP TPLPFQELRL VGGPSRCRGR LEVMHGGSWG SVCDDDWDVV DANVVCRQLG CGLALPVPRP LAFGQGRGPI LLDNVECRGQ EAALSECGSR GWGVHNCFHY EDVAVLCDEF LPTQPPTRKM LTSRAPPTTL PNGKSEGSVR LVGGANLCQG RVEILHSGLW GTVCDDDWGL PDAAVVCRQL GCGAAMAATT NAFFGYGTGH ILLDNVHCEG GEPRLAACQS LGWGVHNCGH HEDAGALCAG LGPPTLTALP SSATREDWAW QTDPSATGVG PQPSRETALL TTAAWAAGKK SGRLRLVGGP GPCRGRVEVL HAGGWGTVCD DDWDFADARV ACREAGCGPA LGATGLGHFG YGRGPVLLDN VGCAGTEARL SDCFHLGWGQ HNCGHHEDAG ALCAGPEELG LQVQQDGSET TRVPTPRPRD GHLRLVNGAH RCEGRVELYL GQRWGTVCDD AWDLRAAGVL CRQLGCGQAL AAPGEAHFGP GRGPILLDNV KCRGEESALL LCSHIRWDAH NCDHSEDASV LCQPS
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