Zinc finger CCCH domain-containing protein 15 (ZC3H15)

About Zinc finger CCCH domain-containing protein 15

Zinc finger CCCH domain-containing protein 15 (ZC3H15) is a protein from Homo sapiens identified by UniProt accession Q8WU90, 426 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

Target properties

Protein name	Zinc finger CCCH domain-containing protein 15
UniProt accession	Q8WU90
Gene	ZC3H15
Organism	Homo sapiens
Length	426 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (30)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
glioblastoma multiforme · score 0.07
gonorrhea · score 0.07
melanoma · score 0.07
neoplasm · score 0.06
hepatocellular carcinoma · score 0.06
insulin resistance · score 0.03
cancer · score 0.02
acute myeloid leukemia · score 0.02
Hepatitis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WU90-F1	alphafold	PREDICTED	71.07	—

Amino-acid sequence (426 residues)

MPPKKQAQAG GSKKAEQKKK EKIIEDKTFG LKNKKGAKQQ KFIKAVTHQV KFGQQNPRQV AQSEAEKKLK KDDKKKELQE LNELFKPVVA AQKISKGADP KSVVCAFFKQ GQCTKGDKCK FSHDLTLERK CEKRSVYIDA RDEELEKDTM DNWDEKKLEE VVNKKHGEAE KKKPKTQIVC KHFLEAIENN KYGWFWVCPG GGDICMYRHA LPPGFVLKKD KKKEEKEDEI SLEDLIERER SALGPNVTKI TLESFLAWKK RKRQEKIDKL EQDMERRKAD FKAGKALVIS GREVFEFRPE LVNDDDEEAD DTRYTQGTGG DEVDDSVSVN DIDLSLYIPR DVDETGITVA SLERFSTYTS DKDENKLSEA SGGRAENGER SDLEEDNERE GTENGAIDAV PVDENLFTGE DLDELEEELN TLDLEE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards