About Ras-related protein Rab-2B
Ras-related protein Rab-2B (RAB2B) is a protein
from Homo sapiens identified by UniProt accession
Q8WUD1, 216 residues long.
MolForge cross-references it against 0 known binders and
26 disease associations.
Target properties
| Protein name | Ras-related protein Rab-2B |
|---|
| UniProt accession | Q8WUD1 |
|---|
| Gene | RAB2B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 216 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (26)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.25
- smoking status measurement · score 0.15
- blood protein measurement · score 0.14
- lean body mass · score 0.11
- fat body mass · score 0.10
- body height · score 0.07
- body weight · score 0.07
- base metabolic rate measurement · score 0.06
- whole body water mass · score 0.05
- mathematical ability · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WUD1-F1 | alphafold | PREDICTED | 87.13 | — |
Amino-acid sequence (216 residues)
MTYAYLFKYI IIGDTGVGKS CLLLQFTDKR FQPVHDLTIG VEFGARMVNI DGKQIKLQIW DTAGQESFRS ITRSYYRGAA GALLVYDITR RETFNHLTSW LEDARQHSSS NMVIMLIGNK SDLESRRDVK REEGEAFARE HGLIFMETSA KTACNVEEAF INTAKEIYRK IQQGLFDVHN EANGIKIGPQ QSISTSVGPS ASQRNSRDIG SNSGCC
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