About Solute carrier family 35 member F5
Solute carrier family 35 member F5 (SLC35F5) is a protein
from Homo sapiens identified by UniProt accession
Q8WV83, 523 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | Solute carrier family 35 member F5 |
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| UniProt accession | Q8WV83 |
|---|
| Gene | SLC35F5 |
|---|
| Organism | Homo sapiens |
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| Length | 523 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (22)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.38
- waist-hip ratio · score 0.30
- monocyte percentage of leukocytes · score 0.30
- calcium measurement · score 0.28
- BMI-adjusted waist circumference · score 0.24
- body height · score 0.14
- metabolite measurement · score 0.09
- isolated hyperchlorhidrosis · score 0.04
- hearing loss-familial salivary gland insensitivity to aldosterone syndrome · score 0.04
- systolic blood pressure · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WV83-F1 | alphafold | PREDICTED | 72.69 | — |
Amino-acid sequence (523 residues)
MVPPRRHRGA GRPGVLSSSP PFRLRSAKFS GIALEDLRRA LKTRLQMVCV FVMNRMNSQN SGFTQRRRMA LGIVILLLVD VIWVASSELT SYVFTQYNKP FFSTFAKTSM FVLYLLGFII WKPWRQQCTR GLRGKHAAFF ADAEGYFAAC TTDTTMNSSL SEPLYVPVKF HDLPSEKPES TNIDTEKTPK KSRVRFSNIM EIRQLPSSHA LEAKLSRMSY PVKEQESILK TVGKLTATQV AKISFFFCFV WFLANLSYQE ALSDTQVAIV NILSSTSGLF TLILAAVFPS NSGDRFTLSK LLAVILSIGG VVLVNLAGSE KPAGRDTVGS IWSLAGAMLY AVYIVMIKRK VDREDKLDIP MFFGFVGLFN LLLLWPGFFL LHYTGFEDFE FPNKVVLMCI IINGLIGTVL SEFLWLWGCF LTSSLIGTLA LSLTIPLSII ADMCMQKVQF SWLFFAGAIP VFFSFFIVTL LCHYNNWDPV MVGIRRIFAF ICRKHRIQRV PEDSEQCESL ISMHSVSQED GAS
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