About EEF1A lysine methyltransferase 1
EEF1A lysine methyltransferase 1 (EEF1AKMT1) is a protein
from Homo sapiens identified by UniProt accession
Q8WVE0, 214 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | EEF1A lysine methyltransferase 1 |
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| UniProt accession | Q8WVE0 |
|---|
| Gene | EEF1AKMT1 |
|---|
| Organism | Homo sapiens |
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| Length | 214 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.31
- self reported educational attainment · score 0.26
- electrocardiography · score 0.19
- intelligence · score 0.18
- insulin like growth factor measurement · score 0.16
- cognitive function measurement · score 0.14
- PR segment · score 0.11
- cystatin C measurement · score 0.10
- PR interval · score 0.09
- appendicular lean mass · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WVE0-F1 | alphafold | PREDICTED | 86.41 | — |
Amino-acid sequence (214 residues)
MSDLEDDETP QLSAHALAAL QEFYAEQKQQ IEPGEDDKYN IGIIEENWQL SQFWYSQETA LQLAQEAIAA VGEGGRIACV SAPSVYQKLR ELCRENFSIY IFEYDKRFAM YGEEFIFYDY NNPLDLPERI AAHSFDIVIA DPPYLSEECL RKTSETVKYL TRGKILLCTG AIMEEQAAEL LGVKMCTFVP RHTRNLANEF RCYVNYDSGL DCGI
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