Pancreatic progenitor cell differentiation and…

About Pancreatic progenitor cell differentiation and proliferation factor-like protein

Pancreatic progenitor cell differentiation and proliferation factor-like protein (PPDPFL) is a protein from Homo sapiens identified by UniProt accession Q8WWR9, 84 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Pancreatic progenitor cell differentiation and proliferation factor-like protein
UniProt accession	Q8WWR9
Gene	PPDPFL
Organism	Homo sapiens
Length	84 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

blood metabolite measurement · score 0.38
serum metabolite measurement · score 0.29
metabolite measurement · score 0.12
appendicular lean mass · score 0.07
central nervous system cancer · score 0.04
amyloid-beta measurement · score 0.03
knee fracture · score 0.03
squamous cell carcinoma · score 0.01
oral squamous cell carcinoma · score 0.01
clear cell renal carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WWR9-F1	alphafold	PREDICTED	61.30	—

Amino-acid sequence (84 residues)

MASVPSIGCL LARNQYYRKS SVSSVSSLTS SDSVNFIDDD KPQQGLPEVA ESTWWFKSFF HSEPVLSNVR IKDLSATGSL SGRS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Pancreatic progenitor cell differentiation and proliferation factor-like protein (PPDPFL)